Four-Piston Diaphragm Pumps

Low-Pulsation, Low-Shear Pump Technology for Biopharmaceutical Fluid Handling

Available TC Series Models

The TC Series includes a range of Four-Piston Diaphragm Pump models covering flow rates from laboratory-scale research to pilot-scale development and production applications.

Selected TC Series models are available as integrated TC-S Smart Pumps, combining the pump head and intelligent controller into a compact platform for laboratory and process development applications.

All models are based on the same proprietary Four-Piston Diaphragm Pump technology platform, providing gentle, low-pulsation, and low-shear fluid transfer with scalable performance across the entire product range.

TC018 quaternary diaphragm pump for biopharmaceutical and laboratory applications

TC-018

Flow rate: 0.005–0.3 L/min
Pressure: 10 bar

TC-180

Flow rate: 0.02–3 L/min
Pressure: 6 bar

TC600 quaternary diaphragm pump for biopharmaceutical and laboratory applications

TC-600

Flow rate: 0.1–10 L/min
Pressure: 6 bar

TC1200 quaternary diaphragm pump for biopharmaceutical and laboratory applications

TC-1200

Flow rate: 0.2–20 L/min
Pressure: 6 bar

TC2500 quaternary diaphragm pump for biopharmaceutical and laboratory applications

TC-2500

Flow rate: 0.4–40 L/min
Pressure: 6 bar

TC-5000

Flow rate: 0.8–80 L/min
Pressure: 6 bar

Overview

The TC Series Four-Piston Diaphragm Pump platform is designed for hygienic bioprocess fluid handling applications requiring gentle, low-shear, and low-pulsation fluid transfer. Its proprietary four-piston technology provides stable flow delivery, self-priming capability, and contamination-controlled operation for sensitive biopharmaceutical fluids.

Engineered for laboratory, pilot-scale, and production environments, the TC Series supports a wide range of applications including chromatography, tangential flow filtration (TFF), buffer preparation, sterile filtration, and other critical bioprocess fluid handling operations.

Why Choose TC Series Four-Piston Diaphragm Pumps

The TC Series is built on Truking Ingenuity’s proprietary Four-Piston Diaphragm Pump technology platform, developed specifically for hygienic bioprocess fluid handling applications.

Its unique four-piston architecture delivers gentle, low-shear, and low-pulsation fluid transfer while providing stable flow delivery, reliable product containment, and long-term operational performance.

Designed for laboratory, pilot-scale, and production environments, the TC Series combines proven engineering with application-focused performance for demanding biopharmaceutical processes.

Key Technical Advantages

Core Design & Structural Differentiation

  • PTFE diaphragms with excellent chemical compatibility and high pressure resistance
  • TC-018 to TC-1200 pump heads withstand up to 10 bar instantaneous pressure shock 
  • Ball-driven transmission design for improved efficiency and higher torque capability 
  • Validated for more than 50 SIP sterilization cycles at 121 °C for 30 minutes

Process & Operational Benefits

  • For gentle, low-pulsation and low-shear transfer of sensitive biologics and aqueous solutions
  • Self-priming operation with low pulsation and stable dry-running capability
  • Linear speed-flow relationship with minimal flow reduction under pressure 
  • Hygienic design suitable for CIP and SIP processes 

Learn more about the four-piston diaphragm pumping principle and how it enables low-shear, low-pulsation, self-priming, and seal-less hygienic fluid transfer.

Customization & OEM System Integration

The TC Series Four-Piston Diaphragm Pump platform can be customized and integrated into a wide range of laboratory, pilot-scale, and production bioprocess systems.

Flexible configuration options support OEM equipment manufacturers and system integrators developing specialized biopharmaceutical fluid handling systems.

  • Custom flow range configurations for specific process requirements
  • Integration with chromatography, filtration, and TFF systems
  • OEM equipment integration for bioprocess skids and laboratory instruments
  • Optional control interfaces and automation compatibility
  • Material and wetted part options for different process fluids

Typical Industries & Applications

The TC Series Four-Piston Diaphragm Pump platform is used throughout biopharmaceutical research, process development, pilot-scale, and manufacturing environments requiring gentle, low-shear, and contamination-controlled fluid transfer.

Typical applications range from laboratory process development to full-scale biopharmaceutical manufacturing, supporting critical fluid handling processes across the entire bioprocess workflow.

Biopharmaceutical Processing

  • Tangential flow filtration (TFF) with low-shear
  • Chromatography and downstream purification
  • Centrifuge feed and aseptic buffer transfer 
  • Sterile and virus filtration

Bioprocess Development

  • Cell culture and protein processing
  • Protein purification
  • Analytical and formulation
  • Vaccine formulation

Laboratory & Pilot Systems

  • Biopharmaceutical laboratory systems
  • Laboratory experiments using diaphragm pumps
  • Pilot-scale bioprocessing systems

Other Hygienic Process Industries

  • Food and beverage processing
  • Cosmetics and personal care manufacturing

Discuss Your Pump Application

Whether you are evaluating the TC Series Four-Piston Diaphragm Pump platform for laboratory, pilot-scale, or production applications, Sainty Flowtech can help you identify the most appropriate TC Series solution for your application.

Discuss your application requirements, TC Series pump selection, system integration, and technology evaluation.

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