
Four-Piston Diaphragm Pumps
Low-Pulsation, Low-Shear Pump Technology for Biopharmaceutical Fluid Handling
Available TC Series Models
The TC Series includes a range of Four-Piston Diaphragm Pump models covering flow rates from laboratory-scale research to pilot-scale development and production applications.
Selected TC Series models are available as integrated TC-S Smart Pumps, combining the pump head and intelligent controller into a compact platform for laboratory and process development applications.
All models are based on the same proprietary Four-Piston Diaphragm Pump technology platform, providing gentle, low-pulsation, and low-shear fluid transfer with scalable performance across the entire product range.

TC-018
Flow rate: 0.005–0.3 L/min
Pressure: 10 bar

TC-180
Flow rate: 0.02–3 L/min
Pressure: 6 bar

TC-600
Flow rate: 0.1–10 L/min
Pressure: 6 bar

TC-1200
Flow rate: 0.2–20 L/min
Pressure: 6 bar

TC-2500
Flow rate: 0.4–40 L/min
Pressure: 6 bar

TC-5000
Flow rate: 0.8–80 L/min
Pressure: 6 bar
Overview
The TC Series Four-Piston Diaphragm Pump platform is designed for hygienic bioprocess fluid handling applications requiring gentle, low-shear, and low-pulsation fluid transfer. Its proprietary four-piston technology provides stable flow delivery, self-priming capability, and contamination-controlled operation for sensitive biopharmaceutical fluids.
Engineered for laboratory, pilot-scale, and production environments, the TC Series supports a wide range of applications including chromatography, tangential flow filtration (TFF), buffer preparation, sterile filtration, and other critical bioprocess fluid handling operations.
Why Choose TC Series Four-Piston Diaphragm Pumps
The TC Series is built on Truking Ingenuity’s proprietary Four-Piston Diaphragm Pump technology platform, developed specifically for hygienic bioprocess fluid handling applications.
Its unique four-piston architecture delivers gentle, low-shear, and low-pulsation fluid transfer while providing stable flow delivery, reliable product containment, and long-term operational performance.
Designed for laboratory, pilot-scale, and production environments, the TC Series combines proven engineering with application-focused performance for demanding biopharmaceutical processes.
Key Technical Advantages
Core Design & Structural Differentiation
- PTFE diaphragms with excellent chemical compatibility and high pressure resistance
- TC-018 to TC-1200 pump heads withstand up to 10 bar instantaneous pressure shock
- Ball-driven transmission design for improved efficiency and higher torque capability
- Validated for more than 50 SIP sterilization cycles at 121 °C for 30 minutes
Process & Operational Benefits
- For gentle, low-pulsation and low-shear transfer of sensitive biologics and aqueous solutions
- Self-priming operation with low pulsation and stable dry-running capability
- Linear speed-flow relationship with minimal flow reduction under pressure
- Hygienic design suitable for CIP and SIP processes
Learn more about the four-piston diaphragm pumping principle and how it enables low-shear, low-pulsation, self-priming, and seal-less hygienic fluid transfer.
Customization & OEM System Integration
The TC Series Four-Piston Diaphragm Pump platform can be customized and integrated into a wide range of laboratory, pilot-scale, and production bioprocess systems.
Flexible configuration options support OEM equipment manufacturers and system integrators developing specialized biopharmaceutical fluid handling systems.
- Custom flow range configurations for specific process requirements
- Integration with chromatography, filtration, and TFF systems
- OEM equipment integration for bioprocess skids and laboratory instruments
- Optional control interfaces and automation compatibility
- Material and wetted part options for different process fluids
Typical Industries & Applications
The TC Series Four-Piston Diaphragm Pump platform is used throughout biopharmaceutical research, process development, pilot-scale, and manufacturing environments requiring gentle, low-shear, and contamination-controlled fluid transfer.
Typical applications range from laboratory process development to full-scale biopharmaceutical manufacturing, supporting critical fluid handling processes across the entire bioprocess workflow.
Biopharmaceutical Processing
- Tangential flow filtration (TFF) with low-shear
- Chromatography and downstream purification
- Centrifuge feed and aseptic buffer transfer
- Sterile and virus filtration
Bioprocess Development
- Cell culture and protein processing
- Protein purification
- Analytical and formulation
- Vaccine formulation
Laboratory & Pilot Systems
- Biopharmaceutical laboratory systems
- Laboratory experiments using diaphragm pumps
- Pilot-scale bioprocessing systems
Other Hygienic Process Industries
- Food and beverage processing
- Cosmetics and personal care manufacturing
Discuss Your Pump Application
Whether you are evaluating the TC Series Four-Piston Diaphragm Pump platform for laboratory, pilot-scale, or production applications, Sainty Flowtech can help you identify the most appropriate TC Series solution for your application.
Discuss your application requirements, TC Series pump selection, system integration, and technology evaluation.
