
TC-5000 Four-Piston Diaphragm Pump
Four-Piston Diaphragm Pump for Laboratory, Pilot-Scale, and Bioprocess Development Applications
Overview
The TC-5000 Four-Piston Diaphragm Pump is designed for laboratory, pilot-scale, and small production bioprocess applications requiring stable, low-pulsation, and low-shear fluid transfer. Its compact hygienic design makes it well suited for chromatography, tangential flow filtration (TFF), buffer preparation, and other sensitive fluid handling processes.
With a flow range of 0.8–80 L/min and a maximum operating pressure of 6 bar, the TC-5000 provides reliable performance across a wide range of process development and pilot-scale applications. Hygienic wetted materials, stable flow delivery, and simple maintenance support dependable long-term operation.
The TC-5000 is available either as an integrated TC-S Smart Pump or as a standalone pump head for OEM equipment and system integration, providing flexibility for both laboratory use and externally controlled bioprocess systems.
Key Technical Advantages
- Gentle, low-shear transfer suitable for sensitive biologics and aqueous solutions
- Very low pulsation characteristics supporting stable high-flow process conditions
- PTFE diaphragm providing excellent chemical resistance and hygienic performance
- Ball-driven transmission design supporting efficient torque transfer and reliable operation
- Linear speed-flow relationship enabling consistent flow performance across operating ranges
- Self-priming capability supporting flexible system integration
- Dry-running capability under appropriate operating conditions
- Hygienic design suitable for CIP and SIP processes
Typical Applications
The TC-5000 is suitable for higher flow sanitary and bioprocess applications, including:
- Biopharmaceutical process fluid transfer
- Buffer and media transfer systems
- Chromatography process integration
- Tangential flow filtration (TFF) processes
- Production-scale process systems
- Integrated sanitary processing equipment
Technical Specifications
| Model | TC-5000S |
| Pump Type | Smart Four-Piston Diaphragm Pump |
| Flow Rate | 0.8-80 L/min |
| Speed Range | 5-800 rpm |
| Voltage | 220V |
| Power | 3KW |
| Max. Operating Pressure: Temperature of Fluid < 40°C (104°F) | 6 bar |
| Max. Operating Pressure: Temperature of Fluid > 40°C (104°F) | 4 bar |
| Maximum Temperature Fluid | 80°C (176°F) |
| Moist Heat Sterilization (SIP) 30 min | 135°C (275°F) |
| Pump Chamber Volume (excluding fittings) | 550 ml |
| Pump Weight with Motor and Housing | 95 kg |
| Connector | TC Clamp ( Ø50) |
| Pump Dimensions with Motor and Housing (L x W x H) | 776 x 320 x 770 mm |
Speed-Flow Characteristics
The figure below shows the speed-flow characteristics of the TC-5000 Four-Piston Diaphragm Pump under different operating pressures using purified water at room temperature as the test medium.
The speed-flow relationship is essentially linear across the operating range, providing stable, predictable, and controllable fluid transfer performance. The TC-5000 operates over a speed range of 5–800 rpm with a maximum flow rate of 80 L/min.

TC5000 speed-flow characteristic curves under different operating pressures
Wetted Materials
| Pump Chamber with Inlet/Outlet Ports | AISI 316L |
| Diaphragm | PTFE |
| Check Valve Diaphragm | EPDM |
| O-Ring | EPDM |
Non-wetted Materials
| Pump Housing | SUS 304 |
| Machined Metal Parts | SUS 304 |
| Screw and Sleeve Nut | SUS 304 |
Environmental Specifications
| Storage & Transportation Temperature Range | 5–55 °C (41-131 °F) |
| Storage & Transportation Humidity Range | 0–50% |
| Operating Temperature Range | 2–40 °C (35.6-104 °F) |
| Operating Humidity Range | 0–50% |
Customization & OEM Integration
The TC Series Four-Piston Diaphragm Pumps are designed for flexible integration into laboratory instruments, OEM equipment, and bioprocess systems requiring precise, low-shear, and hygienic fluid handling.
Configurations are available as integrated TC-S Smart Pumps for standalone laboratory applications or as standalone pump heads for integration into externally controlled process systems.
Sainty Flowtech supports application-specific customization, including control integration, connection configurations, mounting solutions, and other adaptations to facilitate seamless integration into OEM equipment and bioprocess systems.
Discuss Your Pump Application
Contact Sainty Flowtech to discuss your application requirements, TC Series pump selection, system integration, and quotations.
